T&R BIOFAB

Hemostatic Agent

(Matrix Type)

T&R Biofab’s bioabsorbable hemostatic agents prevent excess blood loss in surgery and aids tissue regeneration.

01The unique combination of our proprietary VdECM + hemostatic component (thrombin) + crosslinked gelatin provides hemostasis and mechanical support while sealing the bleeding site.

02Crosslinked gelatin provides a scaffold for blood coagulation and tissue growth

03Absorbed by the body from the sites of implantation without any adverse tissue reaction

Injectable Hydrogels for Orthopedics

T&R Biofab’s biodegradable, injectable and sterile hydrogels relieve pain and induce regeneration of damaged tissue such as ligaments and tendons.

T&R Biofab “OS inject”

Sterilization

Electron Beam

01Hydrogels are the latest innovations for the treatment of orthopedic injuries. These soft, fluid-filled, 3D polymer structures possess rheological and structural properties that allow injection-based administration to the injured site

02Hydrogels provide a biocompatible, biodegradable, and highly hydrated 3D structure that generates physiological cues that mimic the native tissue environment

03Our VdECM contains elastin which promotes cell proliferation, migration, and differentiation for tissue regeneration

04Designed to supply 30-70% of collagen to the damaged area to induce regeneration

05Our formulation allows post-manufacturing sterilization (electron beam technology)

Injectable Drug Delivery Systems

T&R Biofab’s advanced drug delivery system is uniquely designed for sustained drug release of various therapeutic substances.

01Our drug delivery system has thermo-responsive properties that remain at liquid state at room temperature for easy handling and storage and turns into gel at normal body temperature

02The gel property enables a sustained and controlled drug release profile in the body for the duration of the application

03Our drug delivery system is combined with proprietary VdECM to ensure biocompatibility while inside the body and biodegradation. The body naturally degrades the hydrogel after 14 days

04Early results demonstrated 72 hours of sustained release of postoperative pain control medication

05No additional drug modification is required to use T&R Biofab’s proprietary drug delivery system

06Simple and ready to use. Preparation requires little to no training for the clinician.

Anti-adhesion Barrier

Our bioabsorbable and biocompatible anti-adhesion agent can be used as a temporary physical barrier between traumatized tissue surfaces to prevent adhesion during the healing period after surgery.

01Provides a physical barrier to inter-tissue adhesions and inhibits fibroblast migration and ingrowth

02Stays intact within the traumatized tissue until the natural wound healing process is completed, then gets fully absorbed

03Antibiotics serve to (1) suppress inflammation, thereby reducing adhesions, and (2) reduce the risk of infections

04The VdECM contains a large amount of elastin which promotes wound healing before adhesion occurs

05Excellent anti-adhesion coverage: Can be applied even in hard-to-reach areas thanks to its injectable texture. Suitable for laparoscopic procedures

06Easy handling and storage: Liquid state at room temperature and turns into a gel once inside the body